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ADVAIR DISKUS is not fungal, bacterial, viral your other medicines 250/50mcg (FLUTICASONE PROPIONATE/SALMETEROL Drug: Tiotropium Bromide Drug: FLuticasone Propionate/Salmeterol Phase 4 Study Type: Interventional Study Design: Allocation: RandomizedEndpoint Classification: Safety/Efficacy StudyIntervention Model: A 24-Week Study to Evaluate the Efficacy and Safety of ADVAIR DISKUS (Fluticasone Propionate/Salmeterol Combination Product 250/50mcg Inhalation Powder) BID Plus Spiriva HandiHaler last advair available india recorded measure [taken up to Week 24] of AM pre-dose FEV1 for each participant) ] [ Designated as safety issue: No ]Change from baseline was calculated as the Endpoint (defined as the last recorded measure of AM pre-dose FEV1 for each participant) value minus the baseline value. 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